Local penetration of doxorubicin via intrahepatic implantation of PLGA based doxorubicin-loaded implants

• Main Authors: Li Gao (Author), Qingshan Li (Author), Jie Zhang (Author), Yixin Huang (Author), Lin Deng (Author), Chenyang Li (Author), Guangping Tai (Author), Banfeng Ruan (Author)
• Format: Book
• Published: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Doxorubicin (DOX) is widely used in the chemotherapy of a wide range of cancers. However, intravenous administration of DOX causes toxicity to most major organs which limits its clinical application. DOX-loaded drug delivery system could provide a continuous sustained-release of drugs and enables hi...