Decreased Klotho Expression Causes Accelerated Decline of Male Fecundity through Oxidative Injury in Murine Testis

• Main Authors: Ya-Yun Wang (Author), Ying-Hung Lin (Author), Vin-Cent Wu (Author), Yu-Hua Lin (Author), Chia-Yen Huang (Author), Wei-Chi Ku (Author), Chiao-Yin Sun (Author)
• Format: Book
• Published: MDPI AG, 2023-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Oxidative stress is the etiology for 30-80% of male patients affected by infertility, which is a major health problem worldwide. Klotho protein is an aging suppressor that functions as a humoral factor modulating various cellular processes including antioxidation and anti-inflammation, and its dysre...