Unconventional activation of PRKDC by TNF-α: deciphering its crucial role in Th1-mediated inflammation beyond DNA repair as part of the DNA-PK complex

Unconventional activation of PRKDC by TNF-α: deciphering its crucial role in Th1-mediated inflammation beyond DNA repair as part of the DNA-PK complex

Abstract Background The DNA-dependent protein kinase (DNA-PK) complex comprises a catalytic (PRKDC) and two requisite DNA-binding (Ku70/Ku80) subunits. The role of the complex in repairing double-stranded DNA breaks (DSBs) is established, but its role in inflammation, as a complex or individual subu...

Full description

Saved in:
Bibliographic Details
Main Authors: Mohamed A. Ghonim (Author), Jihang Ju (Author), Kusma Pyakurel (Author), Salome V. Ibba (Author), Mai M. Abouzeid (Author), Hamada F. Rady (Author), Shigemi Matsuyama (Author), Luis Del Valle (Author), A. Hamid Boulares (Author)
Format: Book
Published: BMC, 2024-04-01T00:00:00Z.
Subjects:
article
Online Access:Connect to this object online.
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

Connect to this object online.

3rd Floor Main Library

Holdings details from 3rd Floor Main Library
Call Number: A1234.567
Copy 1 Available

Similar Items