Desirability Function in analytical method development for determination of glitazones and metabolites employing HF-LPME

• Main Authors: Matheus Santiago da Silva (Author), Greyce Kelly Steinhorst Calixto (Author), Débora Cristina de Oliveira (Author), Felipe Rebello Lourenço (Author), Leandro Augusto Calixto (Author)
• Format: Book
• Published: Universidade de São Paulo, 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Thiazolidinedione, often shortened to TZD or glitazone, helps lower insulin resistance, which is the underlying problem for many people with type 2 diabetes. The two most known glitazones are pioglitazone (PGZ), with the brand name medicine Actos®, and rosiglitazone (RSG), which is Avandia®...