Development and Validation of a Robust and Efficient HPLC Method for the Simultaneous Quantification of Levodopa, Carbidopa, Benserazide and Entacapone in Complex Matrices

• Main Authors: Erik Wollmer (Author), Sandra Klein (Author)
• Formato: Libro
• Publicado: Frontiers Media S.A., 2017-07-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

Purpose: A variety of fixed-dose combination products is used in the therapy of Parkinson Disease. However, to date a proper analytical method applicable for comparative screening of different antiparkinson products was not available. The objective of the present work was thus to develop and validat...