Lab-scale siRNA and mRNA LNP manufacturing by various microfluidic mixing techniques - an evaluation of particle properties and efficiency
Lipid Nanoparticles (LNPs) are promising drug delivery systems for various RNAs such as small interfering (siRNA) and messenger RNA (mRNA). Microfluidic mixing is a common technique to encapsulate RNA in LNPs. However, high flow rates and lipid concentrations are used for LNP formation to control LN...
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| Main Authors: | , , , , , , , , , |
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| Format: | Book |
| Published: |
Elsevier,
2023-07-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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