Effect of Triptolide on Temporal Expression of Cell Cycle Regulators During Cardiac Hypertrophy

• Main Authors: Jing-Mei Li (Author), Xi-Chun Pan (Author), Yuan-Yuan Ding (Author), Yang-Fei Tong (Author), Xiao-Hong Chen (Author), Ya Liu (Author), Hai-Gang Zhang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Adult mammalian cardiomyocytes may reenter the cell cycle and cause cardiac hypertrophy. Triptolide (TP) can regulate the expressions of various cell cycle regulators in cancer cells. However, its effects on cell cycle regulators during myocardial hypertrophy and mechanism are unclear. This study wa...