Pharmacokinetics, safety, and tolerability of inhaled remdesivir in healthy participants

• Автори: Rita Humeniuk (Автор), Kavita Juneja (Автор), Shuguang Chen (Автор), Scott Ellis (Автор), Olena Anoshchenko (Автор), Deqing Xiao (Автор), Aaron Share (Автор), Matthew Johnston (Автор), Santosh Davies (Автор), Adam DeZure (Автор), Joe Llewellyn (Автор), Anu Osinusi (Автор), Helen Winter (Автор), Sandhya Girish (Автор), Ramesh Palaparthy (Автор), Mark Dresser (Автор)
• Формат: Книга
• Опубліковано: Wiley, 2023-11-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Abstract Intravenous remdesivir (RDV) is US Food and Drug Administration-approved for hospitalized and nonhospitalized individuals with coronavirus disease 2019. RDV undergoes intracellular metabolic activation to form the active triphosphate, GS‐443902, and other metabolites. Alternative administra...