Pharmacokinetics, safety, and tolerability of inhaled remdesivir in healthy participants

• Main Authors: Rita Humeniuk (Author), Kavita Juneja (Author), Shuguang Chen (Author), Scott Ellis (Author), Olena Anoshchenko (Author), Deqing Xiao (Author), Aaron Share (Author), Matthew Johnston (Author), Santosh Davies (Author), Adam DeZure (Author), Joe Llewellyn (Author), Anu Osinusi (Author), Helen Winter (Author), Sandhya Girish (Author), Ramesh Palaparthy (Author), Mark Dresser (Author)
• Format: Book
• Published: Wiley, 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Intravenous remdesivir (RDV) is US Food and Drug Administration-approved for hospitalized and nonhospitalized individuals with coronavirus disease 2019. RDV undergoes intracellular metabolic activation to form the active triphosphate, GS‐443902, and other metabolites. Alternative administra...