Dynamism, Sensitivity, and Consequences of Mesenchymal and Stem-Like Phenotype of Cancer Cells

• Main Authors: Petra Gener (Author), Joaquin Seras-Franzoso (Author), Patricia González Callejo (Author), Fernanda Andrade (Author), Diana Rafael (Author), Francesc Martínez (Author), Sara Montero (Author), Diego Arango (Author), Joan Sayós (Author), Ibane Abasolo (Author), Simó Schwartz (Author)
• Format: Book
• Published: Hindawi Limited, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

There are remarkable similarities in the description of cancer stem cells (CSCs) and cancer cells with mesenchymal phenotype. Both cell types are highly tumorigenic, resistant against common anticancer treatment, and thought to cause metastatic growth. Moreover, cancer cells are able to switch betwe...