Extracts from Argentinian native plants reverse fluconazole resistance in Candida species by inhibiting the efflux transporters Mdr1 and Cdr1

Extracts from Argentinian native plants reverse fluconazole resistance in Candida species by inhibiting the efflux transporters Mdr1 and Cdr1

Abstract Background The development of multidrug resistance (MDR) associated with the overexpression of the efflux transporters Mdr1 and Cdr1 in Candida species impedes antifungal therapies. The urgent need for novel agents able to inhibit the function of both pumps, led us to evaluate this property...

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Bibliographic Details
Main Authors: Florimar Gil (Author), Jerónimo Laiolo (Author), Brayan Bayona-Pacheco (Author), Richard D. Cannon (Author), Antonio Ferreira-Pereira (Author), María Cecilia Carpinella (Author)
Format: Book
Published: BMC, 2022-10-01T00:00:00Z.
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3rd Floor Main Library

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