Disturbed Yin-Yang balance: stress increases the susceptibility to primary and recurrent infections of herpes simplex virus type 1

• Hauptverfasser: Chang Yan (Verfasst von), Zhuo Luo (Verfasst von), Wen Li (Verfasst von), Xue Li (Verfasst von), Robert Dallmann (Verfasst von), Hiroshi Kurihara (Verfasst von), Yi-Fang Li (Verfasst von), Rong-Rong He (Verfasst von)
• Format: Buch
• Veröffentlicht: Elsevier, 2020-03-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Herpes simplex virus type 1 (HSV-1), a neurotropic herpes virus, is able to establish a lifelong latent infection in the human host. Following primary replication in mucosal epithelial cells, the virus can enter sensory neurons innervating peripheral tissues via nerve termini. The viral genome is th...