Efficacy of recombinant adenovirus expressing a fusion gene from GM-CSF and Epstein-Barr virus LMP2A in a mouse tumor model

• Main Authors: Qingjie Xue (Author), Xiuzhen Li (Author), Chunqing Yang (Author), Bingyuan Ji (Author), Yunqing Li (Author), Yingchun Yan (Author), Xinxin Yang (Author), Chunmei Wang (Author), Ting Chen (Author)
• Format: Book
• Published: Taylor & Francis Group, 2017-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In this study, purified GM-CSF and LMP2A mRNAs were amplified by PCR. Then, the GM-CSF and LMP2A sequences were connected by the polypeptide linker (Gly4Ser)3 using gene splicing by overlap extension. The constructed fusion gene GC2A was inserted into the adenovirus vector. Then the recombinant vect...