Heme Oxygenase-1 is critically involved in placentation, spiral artery remodeling and blood pressure regulation during murine pregnancy

• Main Authors: Maria Laura Zenclussen (Author), Nadja eLinzke (Author), Anne eSchumacher (Author), Stefan eFest (Author), Nicole eMeyer (Author), Pablo Ariel Casalis (Author), Ana Claudia Zenclussen (Author)
• Format: Book
• Published: Frontiers Media S.A., 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The onset of pregnancy implies the appearance of a new organ, the placenta. One main function of the placenta is to supply oxygen to the fetus via hemoproteins. In this review, we highlight the importance of the enzyme heme oxygenase-1 (HO-1) for pregnancy to be established and maintained. HO-1 expr...