PTF1a Activity in Enriched Posterior Foregut Endoderm, but Not Definitive Endoderm, Leads to Enhanced Pancreatic Differentiation in an In Vitro Mouse ESC-Based Model

• 主要な著者: Gopika G. Nair (著者), Jon S. Odorico (著者)
• フォーマット: 図書
• 出版事項: Hindawi Limited, 2016-01-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Transcription factors are tools repetitively used by the embryo to generate a variety of lineages. Hence, their context of activation is an important determinant of their ability to specifically trigger certain cell fates, but not others. The context is also consequential when considering directing...