Inhibition of nicotinic acetylcholine receptors by oligoarginine peptides and polyamine-related compounds

Inhibition of nicotinic acetylcholine receptors by oligoarginine peptides and polyamine-related compounds

Oligoarginine peptides, known mostly for their cell-penetrating properties, are also inhibitors of the nicotinic acetylcholine receptors (nAChRs). Since octa-arginine (R8) inhibits α9α10 nAChR and suppresses neuropathic pain, we checked if other polycationic compounds containing amino and/or guanidi...

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Main Authors: Lucy O. Ojomoko (Author), Elena V. Kryukova (Author), Natalya S. Egorova (Author), Arthur I. Salikhov (Author), Lyubov A. Epifanova (Author), Daria A. Denisova (Author), Alex R. Khomutov (Author), Dmitry A. Sukhov (Author), Alexander A. Vassilevski (Author), Maxim A. Khomutov (Author), Victor I. Tsetlin (Author), Irina V. Shelukhina (Author)
Format: Book
Published: Frontiers Media S.A., 2023-12-01T00:00:00Z.
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