Inhibition of nicotinic acetylcholine receptors by oligoarginine peptides and polyamine-related compounds
Oligoarginine peptides, known mostly for their cell-penetrating properties, are also inhibitors of the nicotinic acetylcholine receptors (nAChRs). Since octa-arginine (R8) inhibits α9α10 nAChR and suppresses neuropathic pain, we checked if other polycationic compounds containing amino and/or guanidi...
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Frontiers Media S.A.,
2023-12-01T00:00:00Z.
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A1234.567 |
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