Estimation of dihydroartemisinin in human plasma using a highly sensitive LTQ Orbitrap mass spectrometer with Xcalibur software

Background: Artemether (ARM), the O-methyl ether prodrug of dihydroartemisinin (DHA), is considered a first-line antimalarial agent. Artemether is extensively metabolized in vivo to its active metabolite DHA, and therefore its determination offers considerable difficulties. In the present study, DHA...

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Main Authors: Tareq Abu-Izneid (Author), Muhammad Abbas (Author), David G. Watson (Author), Yasar Shah (Author), Sayyed I. Shah (Author), Fazli Khuda (Author)
Format: Book
Published: Frontiers Media S.A., 2023-05-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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