Rapid Remission With Upadacitinib in a Child With Refractory Crohn's Disease and ATM Mutation: A Case Report

• Principais autores: Yan Liu, MD (Autor), XiaoMei Song, MD (Autor), LingYa Xiang, MD (Autor), Wei Tan, MD (Autor), Min Zou, MD (Autor), Hong Guo, MD (Autor)
• Formato: Livro
• Publicado em: Elsevier, 2024-01-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

ABSTRACT: Managing pediatric Crohn's disease (PCD) presents challenges due to severe complications and higher biologic therapy needs. Transitioning from anti-tumor necrosis factor agents to off-label therapies adds complexity. Although upadacitinib has demonstrated efficacy and tolerability in...