miRNA nanoencapsulation to regulate the programming of the blood-brain barrier permeability by hypoxia

• Main Authors: Esteban G. Figueroa (Author), Aitor Caballero-Román (Author), Josep R. Ticó (Author), Montserrat Miñarro (Author), Anna Nardi-Ricart (Author), Alejandro González-Candia (Author)
• Format: Book
• Published: Elsevier, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Central nervous system (CNS)-related diseases are difficult to treat as most therapeutic agents they cannot reach the brain tissue, mainly due to the blood-brain barrier (BBB), arguably the tightest barrier between the human body and cerebral parenchyma, which routinely excludes most xenobiotic ther...