Population pharmacokinetics and dose rationale for aciclovir in term and pre‐term neonates with herpes

• Hoofdauteurs: S. D'Agate (Auteur), D. Ruiz Gabarre (Auteur), O. Della Pasqua (Auteur)
• Formaat: Boek
• Gepubliceerd in: Wiley, 2024-06-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Abstract Aciclovir is considered the first‐line treatment against Herpes simplex virus (HSV) infections in new‐borns and infants. As renal excretion is the major route of elimination, in renally‐impaired patients, aciclovir doses are adjusted according to the degree of impairment. However, limited a...