Specific chromatin landscapes and transcription factors couple breast cancer subtype with metastatic relapse to lung or brain

• Main Authors: Wesley L. Cai (Author), Celeste B. Greer (Author), Jocelyn F. Chen (Author), Anna Arnal-Estapé (Author), Jian Cao (Author), Qin Yan (Author), Don X. Nguyen (Author)
• Format: Book
• Published: BMC, 2020-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Few somatic mutations have been linked to breast cancer metastasis, whereas transcriptomic differences among primary tumors correlate with incidence of metastasis, especially to the lungs and brain. However, the epigenomic alterations and transcription factors (TFs) which underli...