Strategies for the development of stimuli-responsive small molecule prodrugs for cancer treatment

• Main Authors: Yuxuan Tu (Author), Jianbao Gong (Author), Jing Mou (Author), Hongfei Jiang (Author), Haibo Zhao (Author), Jiake Gao (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Approved anticancer drugs typically face challenges due to their narrow therapeutic window, primarily because of high systemic toxicity and limited selectivity for tumors. Prodrugs are initially inactive drug molecules designed to undergo specific chemical modifications. These modifications render t...