Auranofin, an Anti-rheumatic Gold Drug, Aggravates the Radiation-Induced Acute Intestinal Injury in Mice

• Main Authors: Eun Sang Lee (Author), Joong Sun Kim (Author), Hyounji Lee (Author), Jee-Yeon Ryu (Author), Hae-June Lee (Author), Jong Kyung Sonn (Author), Young-Bin Lim (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pelvic and abdominal radiotherapy plays an important role in eradication of malignant cells; however, it also results in slight intestinal injury. The apoptosis of cells in the intestinal epithelium is a primary pathological factor that initiates radiation-induced intestinal injury. Auranofin, a gol...