Therapeutic effects and mechanisms of N-(9,10-anthraquinone-2-ylcarbonyl) xanthine oxidase inhibitors on hyperuricemia

• Autors principals: Tianshu Gao (Autor), Jin Xu (Autor), Yuxiao Xiao (Autor), Jiaqi Li (Autor), Weifeng Hu (Autor), Xiaoyu Su (Autor), Xudong Shen (Autor), Wan Yu (Autor), Zhen Chen (Autor), Baosheng Huang (Autor), Honglei Li (Autor), Xing Wang (Autor)
• Format: Llibre
• Publicat: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Objective: To observe the antioxidative effects of N-(9,10-anthraquinone-2-ylcarbonyl) xanthine oxidase inhibitors (NAY) in vitro and in vivo models of hyperuricemia and explore the mechanism.Methods: A classical experimental method of acute toxicity and a chronic toxicity test were used to compare...