Geostatistical modelling enables efficient safety assessment for mass drug administration with ivermectin in Loa loa endemic areas through a combined antibody and LoaScope testing strategy for elimination of onchocerciasis.

• Main Authors: Olatunji Johnson (Author), Emanuele Giorgi (Author), Claudio Fronterrè (Author), Benjamin Amoah (Author), Julienne Atsame (Author), Sylvie Ntsame Ella (Author), Marco Biamonte (Author), Kisito Ogoussan (Author), Lee Hundley (Author), Katherine Gass (Author), Peter J Diggle (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The elimination of onchocerciasis through community-based Mass Drug Administration (MDA) of ivermectin (Mectizan) is hampered by co-endemicity of Loa loa, as individuals who are highly co-infected with Loa loa parasites can suffer serious and occasionally fatal neurological reactions from the drug....