Effect of 5-Oxo-2-Pyrrolidinecarboxylic Acid (PCA) as a New Topically Applied Agent for Dry Eye Syndrome Treatment

• Main Authors: Silvia Tampucci (Author), Daniela Monti (Author), Susi Burgalassi (Author), Eleonora Terreni (Author), Erica Zucchetti (Author), Filippo Baldacci (Author), Patrizia Chetoni (Author)
• Format: Book
• Published: MDPI AG, 2018-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The aim of the study was the evaluation of the suitability of 5-oxo-2-pyrrolidinecarboxylic acid (PCA), also in combination with hyaluronic acid (HA), as artificial tears for treatment of dry eye syndrome (DES). Different aqueous formulations containing 0.10% w/w of PCA were used to determine: (i) e...