Neuroprotective and MAOB inhibitory effects of a series of caffeine-8-thioglycolic acid amides

• Asıl Yazarlar: Alexandra Kasabova-Angelova (Yazar), Magdalena Kondeva-Burdina (Yazar), Javor Mitkov (Yazar), Maya Georgieva (Yazar), Virginia Tzankova (Yazar), Alexander Zlatkov (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Universidade de São Paulo, 2020-03-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

The effects of new derivatives of caffeine-8-thioglycolic acid (100 µM) on isolated rat brain synaptosomes, human neuroblastoma cell line SH-SY5Y and human recombinant MAOB enzyme (hMAOB) (1 µM) were evaluated. Most of the compounds, administered alone, didn't show statistically significant neu...