Drug-Induced Liver Injury: Biomarkers, Requirements, Candidates, and Validation

• Main Authors: Lucy Meunier (Author), Dominique Larrey (Author)
• פורמט: ספר
• יצא לאור: Frontiers Media S.A., 2019-12-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

The hepatotoxicity of drugs is the main cause of drug withdrawal from the pharmaceutical market and interruption of the development of new molecules. Biomarkers are useful in several situations. In case of suspected drug-induced liver injury (DILI), biomarkers can be used to confirm liver damage, it...