Gabapentin Prevents Oxaliplatin-Induced Mechanical Hyperalgesia in Mice

• المؤلفون الرئيسيون: Masahiro Ohsawa (مؤلف), Saki Otake (مؤلف), Tomoyasu Murakami (مؤلف), Shohei Yamamoto (مؤلف), Toshiaki Makino (مؤلف), Hideki Ono (مؤلف)
• التنسيق: كتاب
• منشور في: Elsevier, 2014-01-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Abstract.: Oxaliplatin, a platinum-based chemotherapy drug, frequently causes acute and chronic peripheral neuropathies including mechanical hyperalgesia. These adverse effects hinder anticancer therapy with the drug. In this study, we examined several drugs that might prevent oxaliplatin-induced pe...