Gabapentin Prevents Oxaliplatin-Induced Mechanical Hyperalgesia in Mice

• Main Authors: Masahiro Ohsawa (Author), Saki Otake (Author), Tomoyasu Murakami (Author), Shohei Yamamoto (Author), Toshiaki Makino (Author), Hideki Ono (Author)
• Format: Book
• Published: Elsevier, 2014-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract.: Oxaliplatin, a platinum-based chemotherapy drug, frequently causes acute and chronic peripheral neuropathies including mechanical hyperalgesia. These adverse effects hinder anticancer therapy with the drug. In this study, we examined several drugs that might prevent oxaliplatin-induced pe...