Mesenchymal Stem Cells Derived and Cultured from Glioblastoma Multiforme Increase Tregs, Downregulate Th17, and Induce the Tolerogenic Phenotype of Monocyte-Derived Cells

• Main Authors: Kalina Tumangelova-Yuzeir (Author), Emanuil Naydenov (Author), Ekaterina Ivanova-Todorova (Author), Ekaterina Krasimirova (Author), Georgi Vasilev (Author), Sevdalin Nachev (Author), Dobroslav Kyurkchiev (Author)
• Format: Book
• Published: Hindawi Limited, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mesenchymal stem cells (MSCs) possess immunosuppressive properties and have been described in the tumor microenvironment of glioblastoma multiforme (GBM). This manuscript has two major topics-first, to describe isolated and cultured MSCs derived from GBM (GB-MSCs) and second, to examine their in vit...