Soft X-ray Laser Microscopy of Lipid Rafts towards GPCR-Based Drug Discovery Using Time-Resolved FRET Spectroscopy

• Main Authors: Tatsuhiko Kodama (Author), Shin Yoneya (Author), Hiroto Kuroda (Author), Motoyoshi Baba (Author), Kazuyuki Masuda (Author), Takao Hamakubo (Author), Tohru Kozasa (Author)
• Format: Book
• Published: MDPI AG, 2011-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Many signaling molecules involved in G protein-mediated signal transduction, which are present in the lipid rafts and believed to be controlled spatially and temporally, influence the potency and efficacy of neurotransmitter receptors and transporters. This has focus interest on lipid rafts and the...