Development of Arteannuin B Sustained-Release Microspheres for Anti-Tumor Therapy by Integrated Experimental and Molecular Modeling Approaches

• Autors principals: Yanqing Wang (Autor), Weijuan Huang (Autor), Nannan Wang (Autor), Defang Ouyang (Autor), Lifeng Xiao (Autor), Sirui Zhang (Autor), Xiaozheng Ou (Autor), Tingsha He (Autor), Rongmin Yu (Autor), Liyan Song (Autor)
• Format: Llibre
• Publicat: MDPI AG, 2021-08-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Arteannuin B (AB) has been found to demonstrate obvious anti-tumor activity. However, AB is not available for clinical use due to its very low solubility and very short half-life. This study aimed to develop AB long sustained-release microspheres (ABMs) to improve the feasibility of clinical applica...