Development of Arteannuin B Sustained-Release Microspheres for Anti-Tumor Therapy by Integrated Experimental and Molecular Modeling Approaches

• Main Authors: Yanqing Wang (Author), Weijuan Huang (Author), Nannan Wang (Author), Defang Ouyang (Author), Lifeng Xiao (Author), Sirui Zhang (Author), Xiaozheng Ou (Author), Tingsha He (Author), Rongmin Yu (Author), Liyan Song (Author)
• Format: Book
• Published: MDPI AG, 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Arteannuin B (AB) has been found to demonstrate obvious anti-tumor activity. However, AB is not available for clinical use due to its very low solubility and very short half-life. This study aimed to develop AB long sustained-release microspheres (ABMs) to improve the feasibility of clinical applica...