The Triprenylated Anthranoid Ferruginin A, a Promising Scaffold for the Development of Novel Antibiotics against Gram-Positive Bacteria

• Main Authors: Bruno Casciaro (Author), Francesca Ghirga (Author), Floriana Cappiello (Author), Valeria Vergine (Author), Maria Rosa Loffredo (Author), Silvia Cammarone (Author), Elena Puglisi (Author), Carola Tortora (Author), Deborah Quaglio (Author), Mattia Mori (Author), Bruno Botta (Author), Maria Luisa Mangoni (Author)
• Format: Book
• Published: MDPI AG, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In today's post-antibiotic era, the search for new antimicrobial compounds is of major importance and nature represents one of the primary sources of bioactive molecules. In this work, through a cheminformatics approach, we clustered an in-house library of natural products and their derivatives...