Case report: Acute liver failure during deferasirox therapy and the potential role of pharmacogenetics

• Main Authors: Belén García-Fariña (Author), Lydia Rink (Author), Virginia Santarini (Author), Marco Westkemper (Author), Christian Dohna-Schwake (Author), Birte Möhlendick (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background and aimsA number of case reports have documented the occurrence of acute hepatic and renal toxicity during treatment with deferasirox (DFX). The precise mechanisms underlying these adverse events remain unclear, with the time to toxicity varying considerably between patients-some experien...