3,6'- and 1,6'-Dithiopomalidomide Mitigate Ischemic Stroke in Rats and Blunt Inflammation

• Asıl Yazarlar: Yan-Rou Tsai (Yazar), Dong Seok Kim (Yazar), Shih-Chang Hsueh (Yazar), Kai-Yun Chen (Yazar), John Chung-Che Wu (Yazar), Jia-Yi Wang (Yazar), Yi-Syue Tsou (Yazar), Inho Hwang (Yazar), Yukyung Kim (Yazar), Dayeon Gil (Yazar), Eui Jung Jo (Yazar), Baek-Soo Han (Yazar), David Tweedie (Yazar), Daniela Lecca (Yazar), Michael T. Scerba (Yazar), Warren R. Selman (Yazar), Barry J. Hoffer (Yazar), Nigel H. Greig (Yazar), Yung-Hsiao Chiang (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2022-04-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

(<b>1</b>) <b>Background:</b> An important concomitant of stroke is neuroinflammation. Pomalidomide, a clinically available immunomodulatory imide drug (IMiD) used in cancer therapy, lowers TNF-α generation and thus has potent anti-inflammatory actions. Well-tolerated analogs...