Bio-Responsive Carriers for Controlled Delivery of Doxorubicin to Cancer Cells

• Main Authors: Gheorghe Fundueanu (Author), Marieta Constantin (Author), Mihaela Turtoi (Author), Sanda-Maria Bucatariu (Author), Bogdan Cosman (Author), Maria Anghelache (Author), Geanina Voicu (Author), Manuela Calin (Author)
• Format: Book
• Published: MDPI AG, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The cellular internalization of drug carriers occurs via different endocytic pathways that ultimately involve the endosomes and the lysosomes, organelles where the pH value drops to 6.0 and 5.0, respectively. We aimed to design and characterize pH/temperature-responsive carriers for the effective de...