Expression of peroxisome proliferator-activated receptor (PPAR)-α and PPAR-γ in the lung tissue of obese mice and the effect of rosiglitazone on proinflammatory cytokine expressions in the lung tissue

• Main Authors: Seung Lok Ryu (Author), Jae Won Shim (Author), Duk Soo Kim (Author), Hye Lim Jung (Author), Moon Soo Park (Author), Soo-Hee Park (Author), Jinmi Lee (Author), Won-Young Lee (Author), Jung Yeon Shim (Author)
• Format: Book
• Published: Korean Pediatric Society, 2013-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

PurposeWe investigated the mRNA levels of peroxisome proliferator-activated receptor (PPAR)-α, PPAR-γ, adipokines, and cytokines in the lung tissue of lean and obese mice with and without ovalbumin (OVA) challenge, and the effect of rosiglitazone, a PPAR-γ agonist.MethodsWe developed 6 mice models:...