A stability-indicating LC-MS/MS method for zidovudine: Identification, characterization and toxicity prediction of two major acid degradation products

Zidvovudine (AZT) is a nucleoside analogue reverse transcriptase inhibitor (NRTI), a class of anti-retroviral drug. A stability-indicating assay method for AZT was developed in line with ICH guideline. Successful separation of AZT and its degradation products was achieved by gradient elution mode on...

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Main Authors: Prashant S. Devrukhakar (Author), M. Shiva Shankar (Author), G. Shankar (Author), R. Srinivas (Author)
Format: Book
Published: Elsevier, 2017-08-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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