The genome of Mycobacterium africanum West African 2 reveals a lineage-specific locus and genome erosion common to the M. tuberculosis complex.

• Main Authors: Stephen D Bentley (Author), Iñaki Comas (Author), Josephine M Bryant (Author), Danielle Walker (Author), Noel H Smith (Author), Simon R Harris (Author), Scott Thurston (Author), Sebastien Gagneux (Author), Jonathan Wood (Author), Martin Antonio (Author), Michael A Quail (Author), Florian Gehre (Author), Richard A Adegbola (Author), Julian Parkhill (Author), Bouke C de Jong (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2012-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

M. africanum West African 2 constitutes an ancient lineage of the M. tuberculosis complex that commonly causes human tuberculosis in West Africa and has an attenuated phenotype relative to M. tuberculosis.In search of candidate genes underlying these differences, the genome of M. africanum West Afri...