Sinularin Induces Oxidative Stress-Mediated Apoptosis and Mitochondrial Dysfunction, and Inhibits Angiogenesis in Glioblastoma Cells

• Main Authors: Shih-Yuan Hsu (Author), Zhi-Hong Wen (Author), Po-Chang Shih (Author), Hsiao-Mei Kuo (Author), Sung-Chun Lin (Author), Hsin-Tzu Liu (Author), Yi-Hsin Lee (Author), Yi-Jen Wang (Author), Wu-Fu Chen (Author), Nan-Fu Chen (Author)
• Format: Book
• Published: MDPI AG, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Glioblastoma multiforme (GBM) is a cancer of largely unknown cause that leads to a 5-year survival rate of approximately 7% in the United States. Current treatment strategies are not effective, indicating a strong need for the development of novel therapies. In this study, the outcomes of sinularin,...