Quantitative Proteomics Identifies Novel Nrf2-Mediated Adaptative Signaling Pathways in Skeletal Muscle Following Exercise Training

• Main Authors: Anjali Bhat (Author), Rafay Abu (Author), Sankarasubramanian Jagadesan (Author), Neetha Nanoth Vellichirammal (Author), Ved Vasishtha Pendyala (Author), Li Yu (Author), Tara L. Rudebush (Author), Chittibabu Guda (Author), Irving H. Zucker (Author), Vikas Kumar (Author), Lie Gao (Author)
• Format: Book
• Published: MDPI AG, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Exercise training (ExT) improves skeletal muscle health via multiple adaptative pathways. Nrf2 is a principal antioxidant transcription factor responsible for maintaining intracellular redox homeostasis. In this study, we hypothesized that Nrf2 is essential for adaptative responses to ExT and thus b...