Transcriptional Regulation of Neuronal Genes and Its Effect on Neural Functions: NAD-Dependent Histone Deacetylase SIRT1 (Sir2α)

Sir2 (silent information regulator 2) is an NAD-dependent deacetylase that is broadly conserved from bacteria to humans. It catalyzes a unique deacetylation reaction using NAD, and specific inhibitors and activators of its activity have been discovered. In yeast, Sir2 deacetylates histones and parti...

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Main Authors: Shin Hisahara (Author), Susumu Chiba (Author), Hiroyuki Matsumoto (Author), Yoshiyuki Horio (Author)
Format: Book
Published: Elsevier, 2005-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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