MFG-E8 Knockout Aggravated Nonalcoholic Steatohepatitis by Promoting the Activation of TLR4/NF-κB Signaling in Mice

• Main Authors: Jun Hu (Author), Hui Du (Author), Yinglin Yuan (Author), Peipei Guo (Author), Junxia Yang (Author), Xinru Yin (Author), Jin Liu (Author), Shengwang Wu (Author), Jingyuan Wan (Author), Xia Gong (Author)
• Format: Book
• Published: Hindawi Limited, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Nonalcoholic steatohepatitis (NASH) is the common liver disease characterized by hepatic steatosis, inflammation, and fibrosis; there are no approved drugs to treat this disease because of incomplete understanding of pathophysiological mechanisms of NASH. Milk fat globule-epidermal growth factor-fac...