B-cell receptor dependent phagocytosis and presentation of particulate antigen by chronic lymphocytic leukemia cells

• Main Authors: Annabel R. Minton (Author), Lindsay D. Smith (Author), Dean J. Bryant (Author), Jonathan C. Strefford (Author), Francesco Forconi (Author), Freda K. Stevenson (Author), Edd James (Author), Geir Åge Løset (Author), Ludvig A. Munthe (Author), Andrew J. Steele (Author), Graham Packham (Author)
• Format: Book
• Published: Open Exploration Publishing Inc., 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aim: T-helper cells could play an important role in the pathogenesis of chronic lymphocytic leukemia (CLL), a common B-cell neoplasm. Although CLL cells can present soluble antigens targeted from the B-cell receptor to T-helper cells via major histocompatibility complex (MHC) class II, antigens reco...