Synthesis, Structure-Activity Relationships and In Vitro Toxicity Profile of Lactose-Based Fatty Acid Monoesters as Possible Drug Permeability Enhancers

• Κύριοι συγγραφείς: Simone Lucarini (Συγγραφέας), Laura Fagioli (Συγγραφέας), Robert Cavanagh (Συγγραφέας), Wanling Liang (Συγγραφέας), Diego Romano Perinelli (Συγγραφέας), Mario Campana (Συγγραφέας), Snjezana Stolnik (Συγγραφέας), Jenny K. W. Lam (Συγγραφέας), Luca Casettari (Συγγραφέας), Andrea Duranti (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: MDPI AG, 2018-07-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Permeability enhancers are receiving increased attention arising from their ability to increase transepithelial permeability and thus, bioavailability of orally or pulmonary administered biopharmaceutics. Here we present the synthesis and the in vitro assaying of a series of lactose-based non-ionic...