The regulation of Oct4 in human gingival fibroblasts stimulated by cyclosporine A: Preliminary observations

• Main Authors: Cheng-Chia Yu (Author), Chia-Ming Liu (Author), Tai-Chen Lin (Author), Ni-Yu Su (Author), Li-Chiu Yang (Author), Yu-Chao Chang (Author)
• Format: Book
• Published: Elsevier, 2020-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background/purpose: Oct4, a key transcription factor, could reprogram human somatic fibroblasts into embryonic stem cell-like pluripotent cells. The exact mechanism of cyclosporine A (CsA)-induced gingival overgrowth is still unclear. The aim of this study was to investigate the effects of CsA on th...