Detection of 22 common leukemic fusion genes using a single-step multiplex qRT-PCR-based assay

• Main Authors: Xiaodong Lyu (Author), Xianwei Wang (Author), Lina Zhang (Author), Zhenzhu Chen (Author), Yu Zhao (Author), Jieying Hu (Author), Ruihua Fan (Author), Yongping Song (Author)
• Format: Book
• Published: BMC, 2017-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Fusion genes generated from chromosomal translocation play an important role in hematological malignancies. Detection of fusion genes currently employ use of either conventional RT-PCR methods or fluorescent in situ hybridization (FISH), where both methods involve tedious methodo...