Intestinal SIRT3 overexpression in mice improves whole body glucose homeostasis independent of body weight

• Egile Nagusiak: Deepti Ramachandran (Egilea), Rosmarie Clara (Egilea), Shahana Fedele (Egilea), Junmin Hu (Egilea), Endre Lackzo (Egilea), Jing-Yi Huang (Egilea), Eric Verdin (Egilea), Wolfgang Langhans (Egilea), Abdelhak Mansouri (Egilea)
• Formatua: Liburua
• Argitaratua: Elsevier, 2017-10-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Objective: Intestinal metabolism might play a greater role in regulating whole body metabolism than previously believed. We aimed to enhance enterocyte metabolism in mice and investigate if it plays a role in diet-induced obesity (DIO) and its comorbidities. Methods: Using the cre-loxP system, we ov...