Improvement of Duchenne muscular dystrophy phenotype following obestatin treatment

• Main Authors: Jessica González‐Sánchez (Author), Agustín Sánchez‐Temprano (Author), Tania Cid‐Díaz (Author), Regina Pabst‐Fernández (Author), Carlos S. Mosteiro (Author), Rosalía Gallego (Author), Ruben Nogueiras (Author), Xesús Casabiell (Author), Gillian S. Butler‐Browne (Author), Vincent Mouly (Author), José Luis Relova (Author), Yolanda Pazos (Author), Jesús P. Camiña (Author)
• פורמט: ספר
• יצא לאור: Wiley, 2018-12-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Abstract Background This study was performed to test the therapeutic potential of obestatin, an autocrine anabolic factor regulating skeletal muscle repair, to ameliorate the Duchenne muscular dystrophy (DMD) phenotype. Methods and results Using a multidisciplinary approach, we characterized the age...