Hemophagocytosis induced by Leishmania donovani infection is beneficial to parasite survival within macrophages.

• Main Authors: Ayako Morimoto (Author), Kazuyuki Uchida (Author), James K Chambers (Author), Kai Sato (Author), Jing Hong (Author), Chizu Sanjoba (Author), Yoshitsugu Matsumoto (Author), Junya Yamagishi (Author), Yasuyuki Goto (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2019-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Visceral leishmaniasis (VL) is caused by parasitic protozoa of the genus Leishmania and is characterized by clinical manifestations such as fever, hepatosplenomegaly and anemia. Hemophagocytosis, the phenomenon of phagocytosis of blood cells by macrophages, is found in VL patients. In a previous stu...