Familial hypercholesterolemia in Southeast and East Asia

• Autori principali: Candace L. Jackson (Autore), Magdi Zordok (Autore), Iftikhar J. Kullo (Autore)
• Natura: Libro
• Pubblicazione: Elsevier, 2021-06-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Familial hypercholesterolemia (FH) is a relatively common autosomal dominant disorder associated with a significantly increased risk of coronary heart disease (CHD). Most (~85-90%) cases are due to pathogenic variants in the LDL-receptor gene (LDLR), while the remaining are due to pathogenic variant...