Familial hypercholesterolemia in Southeast and East Asia

• Päätekijät: Candace L. Jackson (Tekijä), Magdi Zordok (Tekijä), Iftikhar J. Kullo (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Elsevier, 2021-06-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Familial hypercholesterolemia (FH) is a relatively common autosomal dominant disorder associated with a significantly increased risk of coronary heart disease (CHD). Most (~85-90%) cases are due to pathogenic variants in the LDL-receptor gene (LDLR), while the remaining are due to pathogenic variant...